This article appeared in the New York Times.
For many it appeared to have been a study to disprove the effectiveness of a gluten free diet to treat Autism.
It was a study to show Autistic people had an average amount of gastrointestinal illnesses.
In any scientific test, there must be controls.
It was a small test group followed for 18 years.
I would be more interested in knowing if a larger test group of autistic children, (there are certainly enough to have a 5000 test group), might show significantly larger than normal amounts of gastrointestinal illnesses.
Where and how, were these test subjects found? ( a single location? one city?ethnic group?)
answer: The study subjects were 121 autistic children and 242 other children who were similar in age and sex. All were residents of Olmsted County, Minnesota, home to the Mayo Clinic. Comparing the cumulative incidence, (AS reported in the test subjects medical records), of gastrointestinal problems from birth until the late teens showed that the only significant differences between the two groups were in constipation and feeding issues.
How old were they at the start of the study?
These tests started 18 years ago. What differences would one see in a study started today?
On a less extreme curve than that of Autism, Celiac disease and gastrointestinal disorders are too, on the rise.
Perhaps the study done by the Mayo Clinic on the incidence of gastrointestinal disorders in Autistic populations would have a different outcome if were started today. By using a larger population for the study, where more attention is being paid by pediatricians to the digestive and intestinal problems in autistic children, we might see strong differences in this study and the one just completed. (Children that have been adversely effected by one of the Rotavirus vaccines, used after the study by the Mayo Clinic, which caused severe bowel problems, for example.)
BUT REGARDLESS... WE ARE MORE INTERESTED IN :
how gluten foods effect brain. "Endogenous neurotoxicity" Toxins can occur from substances produced within the body, known as endogenous neurotoxins. An example of an endogenous neurotoxin is the primary neurotransmitter glutamate, which, when levels reach too high, can result in excitotoxicity and cause neuronal death by apoptosis.
Foods can trigger the excess production of glutamate, much the same as a person's diet can trigger his body to manufacturer too much cholesterol. Eating large quantities of meat from cows,( that eat no cholesterol), can result in the excess of cholesterol in the body of the one consuming the meat.
Here are some leads for your research:
http://www.usatoday.com/news/health/2009-07-12-autism13_N.htm
Brain function in the elderly: role of vitamin B12 and folate- ►oxfordjournals.org [PDF]
DG Weir, JM Scott - British medical bulletin, 1999 - British Council
... Brain function, role of vitamin B ]2 and folate ... Folate deficiency is a common presenting
feature of coeliac disease or gluten-sensitive enteropathy, which ...
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… polyphenolics: beneficial effects on aging brain performance and peripheral tissue function
KA Youdim, B Shukitt-Hale, A Martin, H Wang … - Nutritional Neuroscience, 2000 - informaworld.com
... 0 BLUEBERRIES IMPROVE BRAIN FUNCTION ... 89.96 89.96 89.96 Soybean Meal, 48% 49.98 49.98
49.98 Alfalfa Meal, Dehydrated, 17% 19.99 19.99 19.99 Corn Gluten Meal, 60 ...
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Biosynthesis and characteristics of brain protein and ribonucleic acid in mice subjected to …- ►jbc.org [PDF]
CJ Lee - Journal of Biological Chemistry, 1970 - ASBMB
... function or structure. As a measure of brain function, we ... Total. . Fraction C. 151
8.16 36 1.95 2Ooj, Gluten. Brain homogenate.. pH 7.3 supernatant. ...
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[CITATION] Is coeliac disease a potentially treatable cause of liver failure?
FM Stevens, RM McLoughlin - European Journal of Gastroenterology & Hepatology, 2005
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►Effect of intravenous prednisolone in asthmatics with diminished adrenergic responsiveness
… PD NOMOGRAM, D SYNDROME, T FUNCTION … - The Lancet, 1975 - thelancet.com
... of microaneurysms, intramural fibrin, and lipid) and the location of lesions within
the brain all suggest ... 1292. FORM AND FUNCTION OF THE ... 1307. FACTS ABOUT GLUTEN ...
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Anterior insular cortex: linking intestinal pathology and brain function in autism-spectrum …
T Binstock - Medical hypotheses, 2001 - Elsevier
... These treatments include gluten-free and casein-free diets, anti-fungal therapies,
antibiotic therapies ... Intestinal pathology and brain function in autism 715 ...
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… : a comparison of egg albumin, casein, gelatin, soy protein, pea protein, and wheat gluten- ►ajcn.org [PDF]
V Lang, F Bellisle, JM Oppert, C Craplet, FR … - American Journal of Clinical Nutrition, 1998 - Am Soc Nutrition
... tein, pea protein, and wheat protein (gluten). ... In: Heuther G, ed. Amino acid
availability and brain function in health and diseases. ...
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Intestinal pathophysiology in autism- ►ebmonline.org
JF White - Experimental Biology and Medicine, 2003 - SEBM
... etiology of autism is multifactorial. Metabolites of Gluten and Milk Interfere
with Brain Function. According to this theory, it ...
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[CITATION] N-acetylaspartate-A marker of neuronal integrity
EV Sullivan, E Adalsteinsson, DM Spielman, … - Annals of neurology, 2001 - [Boston, Little, Brown and Co.]
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Tyrosine, phenylalanine, and catecholamine synthesis and function in the brain- ►nutrition.org
JD Fernstrom, MH Fernstrom - Journal of Nutrition, 2007 - Am Soc Nutrition
... intake regulation in the weanling rat: effects of the most limiting essential amino
acids of gluten, casein, and ... Branched-chain amino acids and brain function. ...
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http://www.ageofautism.com/2009/07/a-clear-biomarker-for-autism-the-question-of-alterations-in-lipid-metabolism.html
Prostaglandins Leukot Essent Fatty Acids. 2009 Jul 14. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/19608392?ordinalpos=7&itool=EntrezSystem2.
PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum
Detoxify
Diet changes
Bio-med
Physical Intervention Therapy
The A m e r i c a n A u t i s m A s s o c i a t i o n
Organic Excitotoxins
Non-organic neurotoxins
Bisphenol A (BPA), PBDE
Metals
Exogenous toxins
Endogenous neurotoxicity
THERE IS A BIG DIFFERENCE IN WHAT WAS WRITTEN AND WHAT WAS WRITTEN ABOUT
- Actual Study by the Mayo Clinic
" I would link to this if I could find it! "
A New Treatment For Autism:
Cognitive: Sensory input manipulation and feedback.
(c) American Autism Association
Sources of Metal Ingestion
Mercury - Fish, Fructose, Vaccines
Aluminum - Vaccines, Leaching from cooking and canning
Causative
Curative
What is all the fuss? The piont of using a gluten free diet is not to improve, non existant, gastrointestinal disorders.
The point of using a gluten free diet is to improve brain function.
Ongoing Research is in Two parts: Causative and Curative.
Bio feedback
Alternative medicine
Chelating
SCD diet
DAN doctor
Reno ASTRO
